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KMID : 1009020180160030358
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Clinical Psychopharmacology and Neuroscience
2018 Volume.16 No. 3 p.358 ~ p.360
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Ventricular Arrhythmia during Tracheal Intubation and Extubation under General Anesthesia Possibly Induced by Amisulpride: A Case Report
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Fang Bo
Ma Hong
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Abstract
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We are presenting the first documented case of amisulpride related ventricular arrhythmia during tracheal intubation and extubation under general anesthesia in an 48 year-old female with psychiatric history of chronic schizophrenia who was treated with amisulpride. This case suggests the threshold of perioperative arrhythmia is possibly decreased in patients with long-term antipsychotic medication. So, the potential risk of antipsychotics-induced perioperative arrhythmia should be evaluated, as well as heart rhythm monitoring, prophylactic use of antiarrhythmic drugs, and preoperative adjustment of antipsychotics should be considered.
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KEYWORD
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Amisulpride, Ventricular arrhythmia, Intubation, intratracheal
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